Effect of terahertz irradiation on HUVEC cells (ATAC-Seq)

Terahertz (THz) is an electromagnetic wave with a spectrum between microwave and infrared. Due to its unique characteristics, THZ has great application prospects in both medical imaging and biomedicine. however, its effects on the angiogenesis capacity of human umbilical vein endothelial cells (HUVECs) are still unclear. The assay for transposase-accessible chromatin (ATAC) sequencing indicated that the expression of genes related to cytoskeletal increased significantly after THz irradiation. Overall design: In order to explore the effect of terahertz irradiation on angiogenesis, we used 2.52 THz (100 mW/cm2) to irradiate human umbilical vein endothelial cells(HUVECs) for 10 min and then continued to culture for 12 h, and then ATAC sequencing to detect the changes in gene expression