Single-cell and spatial transcriptomic profiling of human glioblastomas

This deposition includes scRNA-seq and Spatial Transcriptomics data for 24 GBM patients, which are categorized as follows: a) 7 patients with newly diagnosed GBM (ND group) b) 5 patients with recurrent GBM (Rec group) c) 12 patients who have undergone neoadjuvant therapy (Neo group). Additionally, this deposition contains scRNA-seq data for both wild-type (WT) and SiglecE knockout (KO) mice bearing intracranial CT2A glioma. The provided data includes both the raw matrix and the processed Seurat objects.