Crystal Structure of PPARgamma Ligand Binding Domain in complex with dibenzooxepine derivative compound-17
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal Structure of PPARgamma Ligand Binding Domain in complex with dibenzooxepine derivative compound-17 Descriptor: 3-[(1~{E})-1-[8-[(8-chloranyl-2-cyclopropyl-imidazo[1,2-a]pyridin-3-yl)methyl]-3-fluoranyl-6~{H}-benzo[c][1]benzoxepin-11-ylidene]ethyl]-4~{H}-1,2,4-oxadiazol-5-one, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Authors: Suzuki, M, Yamamoto, K, Takahashi, Y, Saito, J. Deposit date: 2019-05-07 Release date: 2019-10-30 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Development of a novel class of peroxisome proliferator-activated receptor (PPAR) gamma ligands as an anticancer agent with a unique binding mode based on a non-thiazolidinedione scaffold. Bioorg.Med.Chem., 27, 2019
创建时间：
2019-05-07
