Biogenic signals from plastids and their role in chloroplast development

Chloroplast Defective Mutants

The mutant collection was done starting from the Myouga et al (2013) chloroplast database.  All the genes in their list were confirmed or removed, depending on the updated and available information in literature.
Genes not present in the Myouga database were taken from literature, based on the tables from the two publications from Tadini et al (2020).  Additional genes were searched in the literature.

Table structure.

Detailed information for the mutant characterisation were taken from the main plant databases (TAIR and UniProt) and the corresponding literature.
The table is structured in a way to give an insight into the molecular function of the gene and a description of the mutant phenotype (for both if information was available).
The worksheet "Chloroplast Defective Mutants" contains all the mutants sorted by locus.
The worksheet "Mutants included in Fig.1" depicts all mutants with impairment in essential processes for chloroplast biogenesis and their phenotype is schematically represented with coloured squares in Figure 1.

The last worksheet contains the pie charts, in which the impacts of the main biological functions on the phenotype are visualized.

References:

-Myouga F, Akiyama K, Tomonaga Y, Kato A, Sato Y, Kobayashi M, Nagata N, Sakurai T, Shinozaki K. The Chloroplast Function Database II: a comprehensive collection of homozygous mutants and their phenotypic/genotypic traits for nuclear-encoded chloroplast proteins. Plant Cell Physiol (2013) http://di.org/0.1093/pcp/pcs171
-Tadini L, Jeran N and Pesaresi P, GUN1 and Plastid RNA Metabolism: Learning from Genetics. Cells (2020), 9(10), 2307; https://doi.org/10.3390/cells9102307
-Tadini L, Jeran N, Peracchio C, Masiero S, Colombo M and Pesaresi P, The plastid transcription machinery and its coordination with the expression of nuclear genome: Plastid-Encoded Polymerase, Nuclear-Encoded Polymerase and the Genomes Uncoupled 1-mediated retrograde communication. Phil. Trans. R. Soc. (2020) http://doi.org/10.1098/rstb.2019.0399