Raw data for figure preparation, supplemental files, and supplemental figures: POLD1-based resistance in diverse species
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Figure 1 data: all input text files and R code to create panels A-D of Figure 1; 1 sub folder for each speciesFigure 2 data: all input text files and R code to create panels A & B of Figure 2Supplemental_Figures: Figure S1, S2, S3Supplemental File 1: contains the alignment of each species of interest to cassava POLD1 and the custom perl script used to identify mutation coordinates in cassava POLD1 sequence.Supplemental File 2: The multiple sequence alignment of POLD sequences generated by SIFT for evaluation of mutations on protein function. QUERY: Manes.12G077400; Q9LRE6: <i>Oryza </i><i>sativa subsp. japonica</i> (Rice); O48901: <i>Glycine max</i> (soybean); Q9LVN7: <i>Arabidopsis </i><i>thaliana</i>; O54747: <i>Rattus norvegicus</i> (rat); P97283: <i>Mesocricetus auratus</i> (golden hamster); P28339: <i>Bos taurus</i> (bovine); P28340: <i>Homo sapiens</i> (human); P30316: <i>Schizosaccharomyces pombe</i> (fission yeast); Q54N97: <i>Dictyostelium discoideum </i>(social amoeba); P54358: <i>Drosophila melanogaster</i> (fruit fly); P46588: <i>Candida albicans </i>(yeast); P15436: <i>Saccharomyces cerevisiae</i> (baker’s yeast); P90829: <i>Caenorhabditis </i><i>elegans</i> (nematode); P30315: <i>Plasmodium falciparum</i>; P30315: <i>Paramecium bursaria </i>Chlorella virus NY2A.Supplemental File 3: MP4 movie generated from Chimera showing the POLD1 3D structure from <i>H. sapiens</i> (6NTZ); residues identified in this study are highlighted according to the legend in Fig. 3.Supplemental_File_Descriptions: contains the legends for the Supplemental Files listed above
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2025-09-09



