Trypanothione Reductase from Leishmania infantum in complex with 9a
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6t98
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Trypanothione Reductase from Leishmania infantum in complex with 9a Descriptor: 4-[3-methyl-1-[4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]-3-(2-piperidin-4-ylethoxy)phenyl]-1,2,3-triazol-3-ium-4-yl]butan-1-amine, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... Authors: Carriles, A.A, Hermoso, J.A. Deposit date: 2019-10-26 Release date: 2020-11-18 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity. Eur.J.Med.Chem., 244, 2022
创建时间：
2019-10-26
