Supplementary Material for: Two Case Reports of Adrenal Myelolipoma: Insights into a Rare and Benign Mass

Background: Adrenal myelolipoma (AML) is a rare, benign, and non-functional tumor composed of adipose and hematopoietic tissue. With the increasing use of imaging techniques, AML is more frequently detected as an incidental finding. While small and asymptomatic cases are managed conservatively, larger tumors or symptomatic cases often require surgical intervention, with laparoscopic adrenalectomy emerging as a preferred minimally invasive approach. Case Presentation: This report presents two cases of adrenal myelolipoma diagnosed in a single day at our institution. The first case involved a 53-year-old male with persistent abdominal pain, while the second case was a 61-year-old male with an incidental adrenal mass discovered during imaging for an unrelated procedure. Both patients successfully underwent laparoscopic adrenalectomy, and histopathological analysis confirmed the diagnosis of adrenal myelolipoma. No postoperative complications were observed, and follow-up showed favorable outcomes. Conclusion: AML remains a clinically significant entity due to its varied presentation and potential complications. While traditionally open adrenalectomy was the standard, laparoscopic adrenalectomy is a safe and effective alternative, even for larger tumors, providing benefits such as reduced morbidity. Further research is needed to refine management strategies and long-term outcomes for AML patients.