Crystal structure of 20S proteasome in complex with hydroxylated salinosporamide
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Crystal structure of 20S proteasome in complex with hydroxylated salinosporamide Descriptor: (2R,3S,4R)-2-[(S)-(1S)-cyclohex-2-en-1-yl(hydroxy)methyl]-3-hydroxy-4-(2-hydroxyethyl)-3-methyl-5-oxopyrrolidine-2-carbaldehyde, Proteasome component C1, Proteasome component C11, ... Authors: Groll, M, Arthur, K.A.M, Macherla, V.R, Manam, R.R, Potts, B.C. Deposit date: 2009-06-22 Release date: 2009-09-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition J.Med.Chem., 52, 2009
创建时间：
2009-06-22
