Transcription profiling of human megakaryocytes treated with mild hyperthermia on Mk differentiation

ChEBI2008-06-16 更新2026-07-21 收录

热激应激响应

巨核细胞分化

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-9218 数据链接链接失效反馈

官方服务：

资源简介：

Transcription profiling of human megakaryocytes treated with mild hyperthermia on Mk differentiation

创建时间：

2008-06-16

Gene expression data from human erythroleukemic cells in a time dependent manner after PMA treatment

巨核细胞分化

依赖性基因表达

The molecular regulation of megakaryocytic differentiation is poorly understood. Using a myelogenous leukemia cell line, K562, which can partly recapitulate the process in response to phorbol 12-myri

NIAID Data Ecosystem100

Cell-autonomous function of Runx1 transcriptionally regulates megakaryocytic maturation in mice (expression)

巨核细胞分化

转录因子功能基因组学

RUNX1 transcription factor (TF) is a key regulator of megakaryocytic development and when mutated is associated with familial platelet disorder and predisposition to acute myeloid leukemia (FPD-AML).

NIAID Data Ecosystem50

Additional file 1 of The blood transcriptome of musk deer under heat stress condition reveals the regulatory mechanism of genes to maintain homeostasis metabolism

热激应激响应

代谢调控

Supplementary Material 1: Figure S1: Effects of THI changes on Cl−(A), Ca2+(B), MDA(C), GSH-Px(D), IgG(E) and TNF-α(F) in serum of forestry musk deer; Figure S2: The down-regulated DEGs (A) and up-reu

Figshare2025-04-25 更新40

Megakaryocyte lineage development is controlled by modulation of protein acetylation

巨核细胞分化

蛋白质乙酰化与去乙酰化

Treatment with lysine deacetylase inhibitors (KDACi) for haematological malignancies, is accompanied by haematological side effects including thrombocytopenia, suggesting that modulation of protein ac

NIAID Data Ecosystem80

Notch Stimulates Both Self-Renewal and Lineage Plasticity in a Subset of Murine CD9 High Committed Megakaryocytic Progenitors

巨核细胞分化

Notch信号调控

This study aimed at reinvestigating the controversial contribution of Notch signaling to megakaryocytic lineage development. For that purpose, we combined colony assays and single cells progeny analys

NIAID Data Ecosystem50

Transcription profiling of human megakaryocytes treated with mild hyperthermia on Mk differentiation

资源简介：

相关数据集