IRE1α inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic–ischemic brain injury in rats
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https://hra.figshare.com/articles/IRE1_inhibition_decreased_TXNIP_NLRP3_inflammasome_activation_through_miR-17-5p_after_neonatal_hypoxic_ischemic_brain_injury_in_rats/7877738/1
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资源简介：
IRE1a-induced UPR pathway may contribute to inflammatory activation and brain injury following neonatal HI. IRE1a activation, through decay of miR-17-5p, elevated TXNIP expression to activate NLRP3 inflammasomeand aggravated brain damage.<br><br>
提供机构：
Health Research Alliance
创建时间：
2019-03-21
