PTP1B in complex with a phosphonic acid inhibitor
收藏Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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PTP1B in complex with a phosphonic acid inhibitor Descriptor: MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 1, [{2-bromo-4-[(2R)-3-oxo-2,3-diphenylpropyl]phenyl}(difluoro)methyl]phosphonic acid Authors: Scapin, G, Han, Y, Kennedy, B.P. Deposit date: 2008-04-21 Release date: 2008-06-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor Bioorg.Med.Chem.Lett., 18, 2008
创建时间：
2008-04-21
