Steroid hormone enzyme activities represented by selected steroid hormone metabolite ratios in women with polycystic ovary syndrome compared to healthy women.

The available number of participants (N) and median and 25th-75th quantile are indicated. Between-group differences are determined by Mann–Whitney U test (MWU). Univariable and multivariable models are calculated by linear regression with transformed steroid hormone metabolite as dependent variable. Univariable models contain the PCOS group as predictor variable (with controls as reference group). Multivariable models contain in addition the covariables age and BMI. The β coefficients and the corresponding 95% confidence intervals (CI) are reported on the transformed scale. Note that only significant different ratios are shown here, while the results for all calculated steroid hormones ratios are displayed in S3 Table.