A novel mouse model of hepatocellular carcinoma mediated by hepatitis B virus-specific CD8+ T cells [bulk RNA-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP194744
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资源简介：
We used immunocompetent Fah-/- mice as the recipients and adoptively transferred HBsAg+ hepatocytes from HBs-Tg mice to replace the recipient hepatocytes (HBs-HepR). HBs-HepR mice maintained persistent HBsAg expression with chronic hepatitis and spontaneous liver fibrosis, and eventually developed HCC with a prevalence of 100%. Overall design: Liver tissue mRNA profiles of B6-HepR and HBs-HepR mice after 6 months and 12 months post transfer were generated by deep sequencing using Illumina
创建时间：
2023-04-22
