Zebrafish heart regeneration

Single cell RNA seq of uninjured and injured (wnt-inhibited and non-inhibited) zebrafish hearts accompanied by CRISPR-based lineage tracing obtained by Hu, Lelek, Spanjaard et al. (Nature Genetics 2022).<br> Cell type annotation and cell type color are obtained by the authors. The data was pre-processed to obtain an scvi latent space representation. Growth rates were evaluated using cell cycle marker genes typically used in single cell and the GSEA Hallmark apoptosis geneset and provided in the given adata file. <br> Please cite the original publication: https://www.nature.com/articles/s41588-022-01129-5

该数据集包含未损伤与损伤（经Wnt抑制及未经Wnt抑制）的斑马鱼心脏的单细胞RNA测序（single-cell RNA sequencing, scRNA-seq）数据，以及配套的基于CRISPR（Clustered Regularly Interspaced Short Palindromic Repeats）的谱系追踪结果，由Hu、Lelek、Spanjaard等人于2022年发表于《Nature Genetics》。
细胞类型注释及细胞类型配色方案均由原作者提供。本数据集已完成预处理，以获取scVI潜在空间表征。细胞增殖速率通过常用于单细胞分析的细胞周期标记基因以及基因集富集分析（Gene Set Enrichment Analysis, GSEA）Hallmark细胞凋亡基因集进行评估，相关评估结果已包含在提供的adata文件中。
请引用原文献：https://www.nature.com/articles/s41588-022-01129-5