Cell Painting Gallery

The Cell Painting Gallery is a collection of image datasets created using the Cell Painting assay. The images of cells are captured by microscopy imaging, and reveal the response of various labeled cell components to whatever treatments are tested, which can include genetic perturbations, chemicals or drugs, or different cell types. The datasets can be used for diverse applications in basic biology and pharmaceutical research, such as identifying disease-associated phenotypes, understanding disease mechanisms, and predicting a drug’s activity, toxicity, or mechanism of action (Chandrasekaran et al 2020). This collection is maintained ...

细胞绘画图库（Cell Painting Gallery）是一套基于细胞绘画检测法（Cell Painting assay）构建的图像数据集集合。该数据集的细胞图像通过显微成像技术采集，能够展现各类标记细胞组分在受试处理条件下的响应状态，受试处理可涵盖遗传扰动、化学品或药物，以及不同细胞类型等范畴。此类数据集可广泛应用于基础生物学与药物研发领域的多元场景，例如识别疾病相关表型、解析疾病发病机制，以及预测药物的活性、毒性或作用机制（Chandrasekaran等人，2020）。该数据集集合由博德研究所（Broad Institute）的Carpenter-Singh实验室与Cimini实验室负责维护。面向普通用户的数据集列表、获取指南及其他相关文档可在对应的GitHub页面查阅……

搜集汇总

背景与挑战

背景概述

Cell Painting Gallery是一个包含细胞成像数据集的集合，适用于基础生物学和药物研究，由Broad Institute维护，提供丰富的文档和资源支持。