Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine

This original research article outlines the successful isolation and characterization of the transcriptomic profile of post-ischemic restituting epithelial through a translational pig model. Overall design: Superficial mucosal epithelial cells collected from recovering ischemic jejunum of juvenile pigs were processed for single cell RNA sequencing.