Structure of NUDT15 in complex with 6-thio-GMP
收藏Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Structure of NUDT15 in complex with 6-thio-GMP Descriptor: MAGNESIUM ION, Probable 8-oxo-dGTP diphosphatase NUDT15, [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-sulfanyl-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate Authors: Masuyer, G, Carter, M, Rehling, D, Stenmark, P, Helleday, T, Jemth, A.-S, Valerie, N.C.K, Homan, E, Herr, P, Bevc, L, Page, B.D.G, Hagenkort, A. Deposit date: 2016-08-12 Release date: 2016-08-24 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine. Cancer Res., 76, 2016
创建时间:
2016-08-12



