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singlecell RNA sequencing of lung transplanted human

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE289881
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This dataset contains single-cell RNA sequencing (scRNA-seq) data from human lung transplant recipients.Lung tissue samples were collected from both CLAD patients and donor to assess cellular heterogeneity and gene expression dynamics. Lung tissue samples were obtained from human lung transplant recipients diagnosed with chronic lung allograft dysfunction (CLAD) and from donor. Single-cell suspensions were prepared from these tissues and processed using the 10x Genomics Chromium platform. Raw sequencing data were processed with Cell Ranger, followed by clustering, UMAP visualization, and differential gene expression analysis using Seurat. This experimental design allows for comparative analysis of gene expression profiles between CLAD and control groups. *************************************************************** Raw files for human/patient samples were not submitted to GEO due to concerns about submitting personally identifiable sequence data for open access. ***************************************************************
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2025-09-05
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