Structure of CHK1 10-pt. mutant complex with aminopyrimidine LRRK2 inhibitor
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Structure of CHK1 10-pt. mutant complex with aminopyrimidine LRRK2 inhibitor Descriptor: Serine/threonine-protein kinase Chk1, [4-[[4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-fluoranyl-5-methoxy-phenyl]-morpholin-4-yl-methanone Authors: Dokurno, P, Williamson, D.S, Acheson-Dossang, P, Chen, I, Murray, J.B, Shaw, T, Surgenor, A.E. Deposit date: 2017-08-09 Release date: 2017-10-25 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2 Å) Cite: Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1). J. Med. Chem., 60, 2017
创建时间：
2017-08-09
