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Suppression of statin effectiveness by copper and zinc in yeast and human cells

ChEBI2010-10-29 更新2026-07-21 收录

药物代谢干扰

金属离子毒性

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-25004 数据链接链接失效反馈

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Suppression of statin effectiveness by copper and zinc in yeast and human cells

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2010-10-29

淀粉样变性

金属离子毒性

Russo R, Romeo M, Schulte T, Maritan M, Oberti L, Barzago MM, Barbiroli A, Pappone C, Anastasia L, Palladini G, Diomede L, Ricagno S. Cu(II) Binding Increases the Soluble Toxicity of Amyloidogenic Lig

NIAID Data Ecosystem50

20240305 Gray Figure 3 data

酶抑制活性

金属离子毒性

FIG 3 Copper, zinc, and nickel inhibit RclA activity in vitro. Reactions (500 µl) contained 10 mM HEPES-KOH buffer (pH 7.4), 160 µM NADH, 100 µM HOSCN, and the indicated concentrations of metal salts,

NIAID Data Ecosystem50

Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli

金属离子毒性

蛋白质组学分析

The ability of metal ionophores to induce cellular metal hyperaccumulation endows them with potent antimicrobial activity; however, the targets and mechanisms behind these outcomes are not well unders

NIAID Data Ecosystem40

Organ and tissue distribution of wear products in ovo - OVAPIO

植入物生物力学评估

金属离子毒性

The use of implants in arthroplasty is a common method to restore mobility and quality of life. It was recently shown that orthopaedic implants containing the commonly used CoCrMo alloy can release mi

DataCite Commons2024-05-03 更新50

Effects of metal ions on caspase-1 activation and interleukin-1β release in murine bone marrow-derived macrophages

炎症小体激活

金属离子毒性

Ions released from metal implants have been associated with adverse tissue reactions and are therefore a major concern. Studies with macrophages have shown that cobalt, chromium, and nickel ions can a

Figshare2018-08-23 更新40

Suppression of statin effectiveness by copper and zinc in yeast and human cells

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