Cui2006_CalciumHomeostasis

This a model from the article:
Mathematical modeling of calcium homeostasis in yeast cells.

Cui J, Kaandorp JA. Cell Calcium
2006 Apr;39(4):337-48 16445978
,
Abstract:

In this study, based on currently available experimental observations on protein
level, we constructed a mathematical model to describe calcium homeostasis in
normally growing yeast cells (Saccharomyces cerevisiae). Simulation results show
that tightly controlled low cytosolic calcium ion level can be a natural result
under the general mechanism of gene expression feedback control. The calmodulin
(a sensor protein) behavior in our model cell agrees well with relevant
observations in real cells. Moreover, our model can qualitatively reproduce the
experimentally observed response curve of real yeast cell responding to
step-like disturbance in extracellular calcium ion concentration. Further
investigations show that the feedback control mechanism in our model is as
robust as it is in real cells.
This model was taken from the CellML repository
and automatically converted to SBML.
The original model was:
Cui J, Kaandorp JA. (2006) - version03

The original CellML model was created by:
Lloyd, Catherine, May

[e-mail]
The University of Auckland
The Bioengineering Institute
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