Transcriptional change of HTR8/Svneo cells over expressed with PLAC8-EGFP

The goal of this this project was to study the transcriptional change when PLAC8-EGFP was over expressed in the trophoblast cell line, HTR8/Svneo. Overall design: HTR8/Svneo cells which were stably over expressed with PLAC8-EGFP and EGFP were established.Then trancriptional sequencing experiment was performed to explore the effect of PLAC8 on trophoblast cells.