LncRNA and mRNA expression data from human glioblastoma multiforme

Glioblastoma multiforme(GBM) is the most common and lethal malignant primary brain tumor. Long non-coding RNAs (lncRNAs) are aberrantly expressed in many cancers and are involved in their cell proliferation, apoptosis, angiogenesis, and invasion. To systematically study the role of lncRNAs in GBM, we built gene expression profiles of GBM and non-tumor tissues using lncRNA and mRNA gene expression microarrays. GBM and non-tumor tissues were selected for RNA extraction and hybridization on Affymetrix microarrays. We sought to study the expression profiles of lncRNA and mRNA in GBM and to find potential core genes in the pathogenesis of this high malignant lethal disease.