ShengqingJiangzhuoDecoction Restores the Immunotherapy Response by Reprogramming the IFN-γ/JAK-STAT1/PD-L1 Pathway in Hepatocellular Carcinoma

This dataset contains raw experimental data investigating the mechanism by which ShengqingJiangzhuo Decoction reverses immunotherapy resistance in hepatocellular carcinoma (HCC). It includes:

1. Animal experiment data: Tumor volume measurements, histopathological images (H&E staining), and organ coefficients from mouse models.

2. Flow cytometry data: Raw files (.fcs) for proportions of CD3⁺, CD4⁺, and CD8⁺ T-cell subsets in peripheral blood and spleen.

3. ELISA data: Raw OD values and calculation sheets for serum IFN-γ concentration.

4. Western blot raw images: Full uncropped Western blot images (.tiff) for IFN-γ, JAK1, JAK2, STAT1, IRF1, PD-L1, and GAPDH.

5. Immunohistochemistry images: Original IHC staining images for protein expression in tumor tissues.

6. LC-MS metabolomics data: Raw mass spectrometry data and compound identification tables for chemical composition analysis of ShengqingJiangzhuo Decoction.

This data directly supports the manuscript entitled “ShengqingJiangzhuoDecoction Restores the Immunotherapy Response by Reprogramming the IFN-γ/JAK-STAT1/PD-L1 Pathway in Hepatocellular Carcinoma” and may be used for reproducibility or further analysis.