Atp1a2

ENCODES a protein that exhibits ATP binding; ATPase-coupled monoatomic cation transmembrane transporter activity; P-type sodium:potassium-exchanging transporter activity; INVOLVED IN cellular response to mechanical stimulus; cellular response to steroid hormone stimulus; negative regulation of calcium ion transmembrane transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH Cardiomegaly; hyperhomocysteinemia; hypertension; FOUND IN caveola; dendritic spine; endosome; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol

编码一种展现ATP结合特性的蛋白质；ATP酶偶联的单原子阳离子跨膜转运活性；P型钠-钾交换转运活性；参与细胞对机械刺激的响应；细胞对类固醇激素刺激的响应；负调控钙离子跨膜转运；参与阿替洛尔药代动力学途径；肾上腺素能β受体激动剂和β受体阻滞剂药代动力学途径；阿芬太尼药代动力学途径；与心肥大、高同型半胱氨酸血症、高血压相关；存在于小窝蛋白、树突棘、内质网中；与1-萘基异硫氰酸酯、17α-乙炔雌二醇、17β-雌二醇相互作用。