Crystal structure of human soluble epoxide hydrolase C-terminal domain in complex with a benzohomoadamantane-based urea inhibitor

Crystal structure of human soluble epoxide hydrolase C-terminal domain in complex with a benzohomoadamantane-based urea inhibitor Descriptor: 1-(2,3-dimethoxy-9-methyl-5,6,8,9,10,11-hexahydro-7H-5,9:7,11-dimethanobenzo[9]annulen-7-yl)-3-(1-(tetrahydro-2H-pyran-4-carbonyl)piperidin-4-yl)urea, Bifunctional epoxide hydrolase 2 Authors: Qiu, Q, Prischi, F, Jora, B, Vazquez, S, Conte, M.R. Deposit date: 2024-04-18 Release date: 2025-04-30 Last modified: 2025-11-05 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain. J Enzyme Inhib Med Chem, 40, 2025