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Expression data from ependymal cell cultures treated with MLN4924.. Expression data from ependymal cell cultures treated with MLN4924.

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA436123
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We identified that Foxj1 is degraded by the ubiquitin proteasome system. Foxj1 protein is stabilized by the cullin-RING ligase inhibitor MLN4924. We evaluated global changes to ependymal cell culture gene expression profiles during MLN4924 treatment. Overall design: Fully differentiated ependymal cell cultures (2 weeks old) were either treated with DMSO as a control or with 0.25 uM MLN4924 for 36 hours.
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2018-02-27
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