LIN7, CASK and APBA1 bind

In brain, a complex of three proteins form a tripartite complex which may act to couple synaptic vesicle exocytosis to neuronal cell adhesion. Any of the three protein lin7 homologs A, B or C (LIN7A,B or C) can bind to amyloid beta A4 precursor protein-binding family A member 1 (APBA1 aka MINT1) and peripheral plasma membrane protein CASK (aka LIN2) (Butz et al. 1998). All of these proteins contain PDZ domains, not used in complex formation thus able to recruit adhesion molecules, receptors and channels to the complex.

在大脑中，由三种蛋白质构成的复合体可能形成三联复合物，该复合物可能参与将突触囊泡外排与神经元细胞粘附相耦合的作用。LIN7同源蛋白A、B或C（LIN7A、B或C）中的任何一种均可与淀粉样蛋白β前体蛋白结合家族A成员1（APBA1，亦称MINT1）以及外围质膜蛋白CASK（亦称LIN2）结合（Butz等，1998年）。所有这些蛋白质均含有PDZ结构域，这些结构域在复合物形成中不被使用，因而能够募集粘附分子、受体和通道至复合体中。