MOESM2 of Detecting multiple differentially methylated CpG sites and regions related to dimensional psychopathology in youths

Additional file 2: Table S2. The 100 top-ranked differentially methylated CpGs associated with dimensional psychopathology using all the CpG sites of the EPIC array and included covariates for batch effects. Table S3. The differentially methylated CpGs associated with chronological age in the Philadelphia Neurodevelopmental Cohort (PNC). Table S4. The differentially methylated CpGs (DMPs) associated with the emergence of dimensional psychopathology using batch effects as covariates. Table S5. Overview of significant results from the enrichment analysis obtained using all genes for which the DMPs/DMRs were mapped to or near to the genes. Table S6. Statistics, beta fold change and adjusted p-values for the 663 differentially methylated CpGs (DMPs) associated with the emergence of dimensional psychopathology using batch effects and medication as covariates. Table S7. Gene expression results of genes for which the DMPs were mapped to or near to the genes. Table S8. DNA methylation correlation between brain and blood for DMPs mapped or near to differentially expressed genes. Correlation results are from IMAGE-CpG (Braun, P et al., 2019). Table S9. Information about correlations between: a) the variation of the DNA methylation of the differentially methylated positions (ΔDNAm) and the variation of the expression of genes that were differentially expressed in whole blood (ΔmRNA); b) the variation of the total score of CBCL (ΔCBCL) and ΔDNAm; and c) ΔCBCL and ΔmRNA. The variations were calculated subtracting wave 1 (W1) values from wave 0 (W0) values. Table S10. Differentially methylated regions from DMRCate analysis. Table S11. Gene expression results of genes for which the DMRs were mapped to or near to the genes. Table S12. DNA methytion correlation between brain and blood for CpG site from DMRs mapped or near to differentially expressed genes. Correlation results are from IMAGE-CpG (Braun, P et al., 2019).