MLL-Menin inhibition reverses pre-leukemic progenitor self-renewal induced by NPM1c mutations [ChIP-Seq]. MLL-Menin inhibition reverses pre-leukemic progenitor self-renewal induced by NPM1c mutations [ChIP-Seq]
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
Menin binding to MLL1 is required to maintain self-renewal properties of NPM1c progenitors at different stages of leukemia development Overall design: Mouse NPM1c knock-in cells and human AML cell lines carrying NPM1c mutations were analyzed for the gene expression changes induced by NPM1c and in response to Menin inhibitor VTP-50469.
创建时间：
2019-04-11
