Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 1
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Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 1 Descriptor: ALK tyrosine kinase receptor, N-{1-[cis-4-(hydroxymethyl)cyclohexyl]-5-(piperidin-1-ylmethyl)-1H-benzimidazol-2-yl}-3-(prop-2-en-1-ylsulfamoyl)benzamide Authors: Whittington, D.A, Epstein, L.F, Chen, H. Deposit date: 2012-06-20 Release date: 2012-07-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer. J.Med.Chem., 55, 2012
创建时间：
2012-06-20
