Enrichment analysis results for ECM-related gene lists.

(A) GSEA results for ECM-related gene lists on bulk neutrophil RNA-seq, as a function of age (sex as covariate). Note that no ECM gene set passed significance thresholds for age-related expression. (B) GSEA results for ECM-related gene lists on bulk neutrophil RNA-seq in female vs. male neutrophils (age as covariate). (C) Analysis of significance of overlap for female-biased neutrophil genes by RNA-seq (DEseq2 FDR < 0.05) for ECM related gene list. (D) Limma differential expression analysis of sex-biased proteins in C57BL/6 serum proteomics from [22] (FDR < 0.05). (E) Analysis of significance of overlap for female-biased serum proteins by proteomics (Limma FDR < 0.05) for ECM-related gene list. (XLSX)