Association results on Kosrae for select previously known, associated loci.

1Frayling et al. (2007) Science 316:889.2Loos et al. (2008) Nat Genet 40:768.3Gudbjartsson et al. (2008) Nat Genet 40:609.4Lettre et al. (2008) Nat Genet 40:584.5Kathiresan et al. (2008) Nat Genet 40:189.6Chen et al. (2008) J Clin Invest 118:2620.7Weedon et al. (2005) Diabetes 54:576.8Arnaud-Lopez et al. (2008) Am J Hum Genet 82:12.9Ridker et al. (2008) Am J Hum Genet 82:1185.For SNPs not directly genotyped on the Affymetrix array (n = 9), association results are reported for a proxy on the Affymetrix chip with strong correlation (r2��0.95) to the original SNP in both HapMap Caucasian and Asian populations. The effect size (��) is expressed as the number of standard deviations change in phenotype for each copy of the associated allele. ��Phet �¡� denotes p-values for the test of heterogeneity between the Caucasian and Kosrae effect sizes. SNPs with low frequency in Kosraens (MAFhet Freq��denotes p-values for similarity between frequency of the risk allele in Caucasians and Kosraens. SNPs not directly genotyped on the Affymetrix array were omitted from the comparison of allele frequencies. ��?,�� not analyzed.