Effect of PDE inhibition on basal cytosolic cAMP signal in RASMCs.
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Cytosolic cAMP measurements were conducted in cultured RAMSCs cells using the FRET-based cAMP sensor Epac1-camps. The % increase in CFP/YFP ratio induced by the different PDE inhibitors or the vehicle was calculated after a 3 min-incubation. Data are mean±SEM of 8–13 independent cells as indicated. * P<0.05, ** P<0.01, *** P<0.001 versus vehicle; # P<0.05 versus Ro.
创建时间：
2012-10-18
