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NF-κB- and TET2-mediated macrophage reprogramming overrides the anti-inflammatory effects of hypoxia and improves responses in human cancer

NIAID Data Ecosystem2026-05-02 收录

肿瘤免疫微环境

巨噬细胞编程

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE261324 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-10-10

胃癌预后模型

肿瘤免疫微环境

Gastric cancer (GC) is one of the most common malignant gastrointestinal tumors worldwide. Pyroptosis was widely reported to exert a crucial function in tumor development. In addition, pyroptosis was

NIAID Data Ecosystem10

DataSheet_1_Genomic landscape and expression profile of consensus molecular subtype four of colorectal cancer.zip

结直肠癌分子亚型

肿瘤免疫微环境

BackgroundCompared to other subtypes, the CMS4 subtype is associated with lacking of effective treatments and poorer survival rates. MethodsA total of 24 patients with CRC were included in this study.

NIAID Data Ecosystem00

Absence of Telomerase Leads to Immune Response and Tumor Regression in Zebrafish Melanoma

肿瘤免疫微环境

端粒酶功能

Most cancers reactivate telomerase to maintain telomere length to acquire immortality. The importance of this process is well illustrated by the fact that telomerase promoter mutations are found at a

NIAID Data Ecosystem00

Table2_Bulk- and single cell-RNA sequencing reveal KIF20A as a key driver of hepatocellular carcinoma progression and immune evasion.xlsx

肝癌基因组

肿瘤免疫微环境

IntroductionKinesin family member 20A (KIF20A) is essential for cell proliferation and is implicated in promoting tumor progression, but its role in hepatocellular carcinoma (HCC) remains poorly studi

NIAID Data Ecosystem00

Neutrophils physically interact with cancer cells in breast cancer

肿瘤免疫微环境

中性粒细胞-癌细胞相互作用

We performed RNA-sequencing of single cells and physically interacting cells (PIC-seq) along murine mammary gland development and carcinogenesis. We uncovered that neutrophils appear transiently durin

NIAID Data Ecosystem00

NF-κB- and TET2-mediated macrophage reprogramming overrides the anti-inflammatory effects of hypoxia and improves responses in human cancer

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