Follicle-Stimulating Hormone receptor Antagonist effect on osteoclast maturation and formation

The data set contain information regarding cell viability testing, concentration testing and osteoclast formation. Information was collected using various <i>in vitro </i>techniques including western blotting, resazurin viability testing and tartrate resistant acid phosphatase staining and activity. RAW 264.7 murine macrophages were used as a base which was modified to express wild-type human follicle-stimulating hormone receptor (FSHR). The data set was analyzed using GraphPad Prism 7 and ImageJ. The statistical analysis employed one-way ANOVA and to avoid false positives the Bonferroni correction was utilized in multiple comparisons. No significant conclusions were drawn from the study due to further investigation being required.