首页/数据集/Germline missense MLH1 VUS

Germline missense MLH1 VUS

Figshare2024-05-24 更新2026-04-28 收录

变异功能预测

分子动力学模拟

数据链接：

https://figshare.com/articles/dataset/Germline_missense_MLH1_VUS/25886401 数据链接链接失效反馈

官方服务：

资源简介：

Molecular dynamics simulation of the VUS based on the ClinVar database, the simulation is up to 100 ns.

应用场景：

创建时间：

2024-05-24

分子动力学模拟

血红蛋白功能

Nitrophorin 4 (NP4) is a heme protein that reversibly binds nitric oxide (NO), with release rates modulated by pH change. High-resolution structures of NP4 revealed that pH changes and NO binding indu

NIAID Data Ecosystem60

Multimodal learning of noncoding variant effects using genome sequence and chromatin structure

变异功能预测

表观遗传调控

ncVarPred-1D3D: pretrained models of Sei (PMID: 35817977) + our 3D structure embedding models are shared. The models are trained and validated using DeepSEA (PMID: 26301843) selected 200 bp regions (w

Zenodo2023-08-08 更新00

ParM from plasmid R1 APO form

ParM蛋白结构

分子动力学模拟

ParM from plasmid R1 APO form

NIAID Data Ecosystem00

Pub1-PRE experimental data.zip

蛋白质结构解析

分子动力学模拟

Structure Ensemble of the First Two RNA Recognition Motif Domains of a Poly(U) Binding Protein from Paramagnetic Relaxation Enhancement and Molecular Simulation Guan

Figshare2016-04-21 更新10

RovHer: heritability-optimized scores for the functional prioritization of rare missense variants

变异功能预测

遗传力评估

A heritability-optimized scoring method using multivariate adaptive regression splines that incorporates 75 variant- and gene-level features. RovHer leverages exome-wide association statistics to trai

DataCite Commons2026-05-05 更新00

Germline missense MLH1 VUS

资源简介：

相关数据集