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Structure of human RIPK1 kinase domain in complex with GNE684

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Structure of human RIPK1 kinase domain in complex with GNE684 Descriptor: (5S)-N-[(3S)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 Authors: Fong, R, Lupardus, P.J. Deposit date: 2019-02-11 Release date: 2019-05-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.1 Å) Cite: RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases. Cell Death Differ., 27, 2020

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2019-02-11
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