Sustained expression of cyclin D1 or cyclin D1/KE in mouse mammary gland

ChEBI2013-12-31 更新2026-07-21 收录

乳腺癌细胞周期调控

转基因小鼠肿瘤模型

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Sustained expression of cyclin D1 or cyclin D1/KE in mouse mammary gland

创建时间：

2013-12-31

Genomic aberrations in MMTV-cdc25a;MMTV-neu murine cell line. Mus musculus

肿瘤基因组畸变分析

转基因小鼠肿瘤模型

CDC25A is a critical target of checkpoint, and its overexpression is observed in various cancers. Here we demonstrate that in vivo levels of Cdc25A expression determine the efficiency of transformatio

NIAID Data Ecosystem120

Distinct ErbB-2-coupled signalling pathways promote mammary tumors with unique pathological and transcriptional profiles. Mus musculus

乳腺癌分子病理

转基因小鼠肿瘤模型

ErbB-2 overexpression and amplification occurs in 15 - 30% of human invasive breast carcinomas associated with poor clinical prognosis. Previously, we have demonstrated that four ErbB-2/Neu tyrosine-a

NIAID Data Ecosystem60

Estrogen receptor alpha is cell cycle-regulated and regulates the cell cycle in a ligand-dependent fashion

乳腺癌细胞周期调控

受体信号通路

Estrogen receptor alpha (ERα) has been implicated in several cell cycle regulatory events and is an important predictive marker of disease outcome in breast cancer patients. Here, we aimed to elucidat

NIAID Data Ecosystem60

Expression data of transduced mouse glioblastomas

胶质母细胞瘤基因组学

转基因小鼠肿瘤模型

Transgenic GFAP-, NES-, and SYN- CRE mice were injected with a lenti-viral construct containing a floxed RFP directly upstream of a cassette containing si-p53, GFP, and mutant HRAS. Tumors arising fro

NIAID Data Ecosystem100

Developmental and Lactational Exposure to Dieldrin Alters Mammary Tumorigenesis in Her2/neu Transgenic Mice

乳腺癌环境毒理学

转基因小鼠肿瘤模型

Breast cancer is the most common cancer in Western women and while its precise etiology is unknown, environmental factors are thought to play a role. The organochlorine pesticide dieldrin is a persist

NIAID Data Ecosystem60

Sustained expression of cyclin D1 or cyclin D1/KE in mouse mammary gland

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