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Differentially expressed genes of Peromyscus leucopus fibroblast cultures treated with lipopolysaccharide or buffer alone

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DataONE2021-03-17 更新2025-04-26 收录
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This experiment and its results were part of a larger study of the differential responses of the white-footed deermouse Peromyscus leucopus and the house mouse Mus musculus to single injections of lipopolysaccharide (LPS). The entire study is presented in the associated manuscript in submission and in the listed pre-print. The aim of this particular experiment was to identify differentially expressed genes (DEG) of fibroblast cultures of P. leucopus. The experiment identified 543 DEGs that were either upregulated or down-regulated in response to four hours' exposure to LPS. The accompanying dataset identifies these DEGs and gives the fold-change of LPS-treated over control samples as well as the false-discovery rate (FDR) p value. For protein coding sequences the 10 highest TPMs in order among control samples were ferritin heavy chain (Fth), Slpi, secreted protein acidic and cysteine rich (Sparc), eukaryotic translation elongation factor 1 alpha (Eef1a1), ferritin light chain (Ftl), ...
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2025-04-23
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