Converging evidence indicates that dysfunctions in glutamatergic neurotransmission and in the glutamate-glutamine cycle play a role in the pathophysiology of schizophrenia. Here, we investigated gluta
BackgroundSchizophrenia (SCZ) is a debilitating neuropsychiatric disorder with unclear etiology, involving complex interactions between genetic and environmental factors. Current diagnostic methods re
The study profiles genome-wide miRNA expression in blood from 15 early-onset SZ (EOS) cases and 15 healthy controls. A total of 1070 miRNAs were detected by the microarrays in our samples. We profiles
Shown are miRNAs (Experiment 1) which differed from controls by t-test at pTable 2) are shown in bold. The synaptic enrichment ratio was calculated from deep sequencing data (Experiment 2) based on it