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Organocatalyzed Asymmetric Aldol Reactions of Ketones and β,γ‑Unsaturated α‑Ketoesters and Phenylglyoxal Hydrates

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https://figshare.com/articles/dataset/Organocatalyzed_Asymmetric_Aldol_Reactions_of_Ketones_and__Unsaturated_Ketoesters_and_Phenylglyoxal_Hydrates/2215054
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资源简介:
Enantioselective aldol reactions of acetophenone with β,γ-unsaturated α-ketoesters and cyclic ketones with phenylglyoxal hydrates were realized with cinchona alkaloid-derived thiourea catalysts. The corresponding aldol products were obtained in high yields and good to excellent diastereoselectivities and enantioselectivities (up to 95% ee).
创建时间:
2016-02-15
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