thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+

Cytosolic dihydropyrimidine dehydrogenase catalyzes the reaction of thymine and NADPH + H+ to form 5,6-dihydrothymine and NADP+. The mechanism of the human reaction is inferred from that of the well-characterized pig enzyme (Yokota et al. 1994).

细胞质二氢嘧啶脱氢酶催化胸腺嘧啶与NADPH + H+的反应，生成5,6-二氢胸腺嘧啶和NADP+。人类反应机制推断自已充分表征的猪酶（Yokota 等，1994年）。