Examples of occurrence of the Lavalette distribution.

The file S1_File.rar contains the data we used to illustrate the occurrence of the Lavalette distribution. The files nigeria-tau.txt and spain-tau.txt consist of the population data sets of Spain and Nigeria analyzed in this work. Missense variants utilized to calculate amino-acid to amino-acid rates are in the file 1000G-matrix.txt. The files mammalian-no-organelle.txt and plant-organelle.txt contain the codon usage information in mammalian and plant organelle nucleus respectively. (RAR)