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Structure of 14-3-3 isoform sigma in complex with a C-Raf1 peptide and a stabilizing small molecule fragment

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Structure of 14-3-3 isoform sigma in complex with a C-Raf1 peptide and a stabilizing small molecule fragment Descriptor: 14-3-3 binding site peptide of RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, 6,6-dihydroxy-1-methoxyhexan-2-one Authors: Ottmann, C, Rose, R, Kaiser, M, Kuhenne, P. Deposit date: 2010-08-03 Release date: 2010-09-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling Mol.Cell.Biol., 30, 2010
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2010-08-03
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