Versatile Cobalt-Catalyzed Enantioselective Entry to Boryl-Functionalized All-Carbon Quaternary Stereogenic Centers
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https://figshare.com/articles/dataset/Versatile_Cobalt-Catalyzed_Enantioselective_Entry_to_Boryl-Functionalized_All-Carbon_Quaternary_Stereogenic_Centers/6987308
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资源简介：
We report an asymmetric synthesis
of chiral boryl-functionalized
γ-lactams containing all-carbon quaternary stereocenters via
a Co-catalyzed enantioselective hydroboration/cyclization of amide-tethered
1,6-enynes. These enantio-enriched γ-lactam products can be
readily converted to a variety of cyclic and acyclic other chiral
γ-lactams, pyrrolidin-2,3-diones, β-amino acid N-carboxyanhydrides, and β-amino carboxylic amides.
创建时间：
2018-08-20
