Effects of high cholesterol diet on intimal transcriptome [Intima_mRNA]
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP397159
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Purpose: To investigate the effects of high cholesterol diet on the intimal transcriptome related to atherosclerosis. Methods: 3-week-old LDLR-/- male mice were fed a high cholesterol or low cholesterol diet for 9 weeks. Intimal RNA was extracted by injecting Trizol into the aorta and collecting the flow through for further processing. Results: Mice fed a high cholesterol revealed upregulation in atherosclerosis and immune/inflammatory related genes. Overall design: Intimal mRNA and small RNA were sequenced from LDLR-/- male mice after 9 weeks of low cholesterol or high cholesterol feeding. This dataset includes the intimal mRNA data.
创建时间：
2023-05-11
