Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells [PRO-seq early]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE194345
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资源简介：
We acutely depleted the BCL11A protein by using the dTAG PROTAC technology, and assessed its immediate consequences on nascent transcription, DNA methylation, Protein expression and HIstone modification and chromatin accessibility. Examination of changes in Nascent transcription that occur imminently upon depletion of the repressive transcription factor BCL11A in two clones.
创建时间：
2022-07-20
