database of Disease-Gene Associations with annotated Relationships

The database of Disease-Gene Associations with annotated Relationships (eDGAR) is a database for collecting and organizing the data on gene/disease associations as derived from OMIM, Humsavar and ClinVar. For each heterogeneous or polygenic disease, eDGAR provides information on the relationship among the proteins encoded by the involved genes, including transcription factors and protein-protein interactions.

带注释关联关系的疾病-基因关联数据库（eDGAR）是一款用于收集、整理源自OMIM、Humsavar及ClinVar的基因-疾病关联数据的专业数据库。针对每一种异质性疾病或多基因疾病，eDGAR会提供相关基因所编码的蛋白质之间的相互关联信息，涵盖转录因子及蛋白质-蛋白质相互作用相关内容。

搜集汇总

背景与挑战

背景概述

eDGAR是一个免费开放的数据库，专门收集和整理来自OMIM、HUMSAVAR和CLINVAR的基因与疾病关联数据。它为异质或多基因疾病提供基因编码蛋白间的关系信息，包括转录因子和蛋白质-蛋白质相互作用，并为每个基因提供现有注释。