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Integration of the ISCR1 element and its nearby sequences, including the blaNDM-1 gene region, into a class 1 integron.

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Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Integration_of_the_IS_CR1_element_and_its_nearby_sequences_including_the_blaNDM_1_gene_region_into_a_class_1_integron_/1148781
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The circular transposition intermediate generated by ISCR1 is shown above. Integration at the sul1 locus of a class 1 integron resulted in the genetic environment identified as flanking the blaNDM-1 ‘common neighbourhood’ region in pLK75 and pLK78 (pLK78 is shown here). The remarkable features are indicated: IRs, inverted repeats; IntI, integrase gene of class 1 integron; ISCR1 (orf513), integrase gene of ISCR1; oriIS, origin of replication of the ISCR element.
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2016-02-23
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